A groundbreaking 2011 paper by neurologist and researcher Ethan Russo described the way cannabinoids and terpenes work together to boost and modulate the effects of one another in the body's endocannabinoid system (ECS).
For a long time THC was considered the only chemical of psychoactive importance in cannabis. Russo and team helped reveal how other cannabinoids (like CBD) and terpenes can either increase or decrease the effects of THC and other chemicals in the body that interact with the ECS.
- Myrcene, for instance, potentiates (increases) the effects of THC, induces sedation (sleepiness) and provides anti-inflammatory, anti-cancer and analgesic (anti-pain) effects.
- Limonene, on the other hand, is an energizing anti-depressant.
The difference between an energetic and uplifting high compared to a sedating and relaxing high is a factor of the terpenes within the strain.